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Archive entry:
9789811047534 - Bin Zhuang: Development of a Fully Integrated "Sample-In-Answer-Out" System for Automatic Genetic Analysis - Book

Bin Zhuang (?):

Development of a Fully Integrated "Sample-In-Answer-Out" System for Automatic Genetic Analysis (2017) (?)

Delivery from: AustraliaBook is in english languageNew bookeBook, e-Book, digital bookproduct for digital download
ISBN:

9789811047534 (?) or 9811047537

, in english, Springer, Springer, Springer, New, ebook, digital download
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This thesis reports on the development of a fully integrated and automated microsystem consisting of low-cost, disposable plastic chips for DNA extraction and PCR amplification, combined with a reusable glass capillary array electrophoresis chip, which can be employed in a modular-based format for genetic analysis. In the thesis, DNA extraction is performed by adopting a filter paper-based method, followed by an "in-situ" PCR carried out directly in the same reaction chamber of the chip without elution. PCR products are then co-injected with sizing standards into separation channels for detection using a novel injection electrode. The entire process is automatically carried out by a custom-made compact control and detection instrument. The author thoroughly tests the system's performance and reliability by conducting rapid genetic screening of mutations on congenital hearing loss and pharmacogenetic typing of multiple warfarin-related single-nucleotide polymorphisms. The successful development and operation of this microsystem establishes the feasibility of rapid "sample-in-answer-out" testing in routine clinical practice.
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Category: Technology
Keywords: Development of a Fully Integrated "Sample-In-Answer-Out" System for Automatic Genetic Analysis Bin Zhuang Adult Technology 9789811047534
Data from 08/03/2017 01:35h
ISBN (alternative notations): 981-10-4753-7, 978-981-10-4753-4
Archive entry:
9789811047534 - Development of a Fully Integrated Sample-In-Answer-Out System for Automatic Genetic Analysis als eBook von Bin Zhuang - Book

Development of a Fully Integrated Sample-In-Answer-Out System for Automatic Genetic Analysis als eBook von Bin Zhuang (?)

Delivery from: GermanyNew bookeBook, e-Book, digital bookproduct for digital download
ISBN:

9789811047534 (?) or 9811047537

, unknown language, New, ebook, digital download
Development of a Fully Integrated Sample-In-Answer-Out System for Automatic Genetic Analysis ab 87.99 EURO Springer Theses, Development of a Fully Integrated Sample-In-Answer-Out System for Automatic Genetic Analysis ab 87.99 EURO Springer Theses
Category: eBooks > Sachthemen & Ratgeber > Technik
Data from 08/03/2017 01:35h
ISBN (alternative notations): 981-10-4753-7, 978-981-10-4753-4

9789811047534

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