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Archive entry:
9789811047527 - Bin Zhuang: Development of a Fully Integrated "Sample-In-Answer-Out" System for Automatic Genetic Analysis - Book

Bin Zhuang (?):

Development of a Fully Integrated "Sample-In-Answer-Out" System for Automatic Genetic Analysis (?)

Delivery from: United States of AmericaThis book is a hardcover book not a paperbackNew book
ISBN:

9789811047527 (?) or 9811047529

, unknown language, Springer Singapore, hardcover, New
In Stock, plus shipping
Development-of-a-Fully-Integrated-Sample-In-Answer-Out-System-for-Automatic-Genetic-Analysis~~Bin-Zhuang, Development of a Fully Integrated "Sample-In-Answer-Out" System for Automatic Genetic Analysis, hardcover
Category: Science>Engineering>Engr Ref
Data from 05/04/2017 20:33h
ISBN (alternative notations): 981-10-4752-9, 978-981-10-4752-7
Archive entry:
9789811047527 - Development of a Fully Integrated "Sample-in-Answer-Out" System for Automatic Genetic Analysis 2017 - Book

Development of a Fully Integrated "Sample-in-Answer-Out" System for Automatic Genetic Analysis 2017 (?)

Delivery from: United Kingdom of Great Britain and Northern IrelandBook is in english languageNew book
ISBN:

9789811047527 (?) or 9811047529

, in english, New
in-stock
This thesis reports on the development of a fully integrated and automated microsystem consisting of low-cost, disposable plastic chips for DNA extraction and PCR amplification, combined with a reusable glass capillary array electrophoresis chip, which can be employed in a modular-based format for genetic analysis. In the thesis, DNA extraction is performed by adopting a filter paper-based method, followed by an in-situ PCR carried out directly in the same reaction chamber of the chip without elution. PCR products are then co-injected with sizing standards into separation channels for detection using a novel injection electrode. The entire process is automatically carried out by a custom-made compact control and detection instrument. The author thoroughly tests the system s performance and reliability by conducting rapid genetic screening of mutations on congenital hearing loss and pharmacogenetic typing of multiple warfarin-related single-nucleotide polymorphisms. The successful development and operation of this microsystem establishes the feasibility of rapid sample-in-answer-out testing in routine clinical practice.
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Data from 05/04/2017 20:33h
ISBN (alternative notations): 981-10-4752-9, 978-981-10-4752-7

9789811047527

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